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In case testosterone enanthate of these symptoms should immediately seek medical attention. Be aware that symptoms such as agitation, akathisia or mania may be associated with the underlying disease or be a consequence of the applied therapy. If you have symptoms of clinical deterioration (including new symptoms) and / or suicidal ideation / behavior, especially in case of sudden they appear, the growth of the severity of symptoms, or if they were not part of the preceding symptom in a given patient, it is necessary to review the regimen until .

Drug withdrawal akathisiaOccasionally treatment with paroxetine or other drug group of selective inhibitors of serotonin reuptake (SSRIs) are accompanied by the emergence of akathisia, which is evident sense of inner restlessness and agitation, when the patient can not sit or stand; with akathisia. the patient usually experiences a subjective discomfort. Probability of akathisia is highest in the first few weeks of treatment. Serotonin syndrome / neuroleptic malignant syndrome In rare cases, treatment with paroxetine may serotonin syndrome or symptoms such neuroleptic malignant syndrome, especially paroxetine used in combination with other serotonergic agents and / or antipsychotics.

These syndromes represent a potential threat to life and, therefore, treatment with paroxetine should be discontinued in the event of their occurrence (they are characterized by groups of symptoms such as hyperthermia, muscle rigidity, myoclonus, autonomic dysfunction with possible rapid changes in indicators of vital signs, mental status changes, including confusion, irritability, extreme severe agitation, progressing to delirium and coma), and start supporting testosterone enanthate symptomatic therapy. Paroxetine should not be administered in combination with serotonin precursors (such as L-tryptophan, oksitriptan) due to the risk of developing the syndrome serotoninergicheskogog.

Mania and bipolar disorder, major depressive episode may be the initial manifestation of bipolar disorder. It is believed (although not proven controlled trials) that treating such an episode antidepressant alone may increase the likelihood of accelerated development of a mixed / manic episode in patients at risk for bipolar disorder. Before starting treatment with an antidepressant is necessary to conduct a thorough screening to assess the risk of occurrence of a given patient of bipolar disorder; such screening should include gathering a detailed psychiatric history, including information about the presence of a family history of suicide, bipolar disorder and depression. Paroxetine is not registered for the treatment of depressive episodes in bipolar disorder. Paroxetine should be used with caution in patients with a history of mania. Monoamine oxidase inhibitors (MAOIs), paroxetine treatment should be started cautiously not earlier than 2 weeks after discontinuation of MAO inhibitors; paroxetine the dose should be increased gradually until the optimal therapeutic effect.

Renal or hepatic function
is recommended to be careful in the treatment of paroxetine patients with severe renal impairment and in patients with impaired hepatic function. Epilepsy As with other antidepressants, paroxetine should be used with caution in patients with epilepsy. Seizures frequency of seizures in patients taking paroxetine, is less than 0.1%. In case of convulsive seizure treatment with testosterone enanthate paroxetine should be discontinued.

Electroconvulsive therapy There is only limited experience with the simultaneous use of paroxetine and electroconvulsive therapy. Glaucoma As with other drugs of the SSRI, paroxetine causes mydriasis and should be used with caution in patients with narrow-angle glaucoma. Hyponatremia When treating paroxetine hyponatremia is rare, and mostly in elderly patients and leveled after the abolition of paroxetine. haemorrhage reported hemorrhages in skin and mucous membranes (including gastrointestinal bleeding) in patients while taking paroxetine. Therefore, you should paroxetine used with caution in patients who simultaneously receive drugs that increase the risk of bleeding in patients with a known tendency to bleeding and in patients with diseases predisposing to bleeding. Heart disease is the usual precautions should be observed when treating patients with heart disease.

Symptoms that may occur when you stop treatment with paroxetine in adults: . as a result of clinical trials in adults the incidence of adverse events with the abolition of paroxetine was 30%, whereas the incidence of adverse events in the placebo group was 20% describe such withdrawal symptoms as dizziness, sensory disturbances testosterone enanthate ( including paresthesia, sensation of electric shock and tinnitus), sleep disturbances (including intense dreams), agitation or anxiety, nausea, tremor, confusion, sweating, headache and diarrhea. steroiden kaufen

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