Fertility SSRIs (including paroxetine) may affect the quality of semen. This effect is reversible after discontinuation of the drug. Change sperm characteristics may cause impairment of fertility.
Pregnancy Animal studies have not revealed at Paroxetine teratogenic or selective embryotoxic activity. Recent epidemiological studies of pregnancy outcomes when taking antidepressants during the first trimester showed an increased risk of congenital anomalies, particularly cardiovascular (eg, defects testosterone enanthate dosage ventricular and atrial walls) associated with taking paroxetine.
According to the occurrence of cardiovascular defects when used during pregnancy paroxetine approximately 1/50, whereas the expected occurrence of such defects in the general population is approximately 1/100 infants. In the appointment of paroxetine should be considered an alternative treatment in pregnant women and women planning pregnancy. There are reports of premature birth in women who received paroxetine during pregnancy, or other SSRI drugs, but a causal relationship between these drugs and preterm birth has not been established. Paroxetine should not be used during pregnancy if the potential benefit is less than the possible risk.
It should be especially careful to watch the state of health of those newborns whose mothers took paroxetine in late pregnancy, as there are reports of complications in neonates exposed to paroxetine or other medications SSRIs in the third trimester of pregnancy. It should be noted, however, that in this case, the causal relationship between these complications and that medical therapy has not been established.
Described clinical complications included: respiratory distress, cyanosis, apnea, seizures, temperature instability, difficulty in feeding, vomiting, hypoglycemia, hypertension, hypotension, hyperreflexia, tremor, trembling, nervous excitability, irritability, lethargy, constant crying and somnolence . Some reports have been described as symptoms of neonatal withdrawal symptoms. In most cases, described complications arose immediately after birth or shortly thereafter (<24 hours). According to epidemiological studies taking medication SSRIs (including paroxetine) in late pregnancy is associated with increased risk of neonatal pulmonary hypertension persistiruyushey. The testosterone enanthate dosage increased risk observed in children born to mothers who took SSRIs late in pregnancy, is 4-5 times higher than observed in the general population (1-2 per 1000 pregnancies). Lactation In breast milk penetrate small amounts of paroxetine. Nevertheless, paroxetine should not be taken during breastfeeding except in cases where its benefits to the mother outweigh the potential risks for the child.
Effects on ability to drive and / or other mechanisms
Clinical experience with paroxetine indicates that it does not impair cognitive and psychomotor functions. However, as in the treatment of any other psychotropic drugs patients should be particularly careful when driving and operating machinery.
Despite the fact that paroxetine testosterone enanthate dosage does not increase the negative effects of alcohol on psychomotor functions, at the same time is not recommended to use paroxetine and alcohol. buy anabolic steroids online bruce lee’s workout anabolic steroids online uk